In December 2022, the U.S. Environmental Protection Agency (U.S. EPA) made final revisions to the risk assessment for PCE under the Toxic Substances Control Act (TSCA). Perchloroethylene (PCE) is considered a whole chemical substance and is assessed to pose an unreasonable risk to human health under the circumstances of its use.
According to the September 2020 revised risk assessment determination, EPA found that PCE poses an unreasonable risk to workers and non-user labor (workers in close proximity to but not directly exposed to chemicals), consumers, and bystanders. The EPA determined that PCE poses an unreasonable risk to workers and non-users (workers in close proximity to but not directly exposed to chemicals), consumers and bystanders. The EPA determined that PCE poses a risk of adverse health (non-cancer) effects, including neurotoxicity and liver effects from acute and chronic inhalation and skin exposure to PCE; in addition, the EPA determined that chronic inhalation and skin exposure to PCE poses a risk of cancer. Overall, the EPA determined that 60 of the 61 use scenarios pose an unreasonable risk.
Original Source: EPA Finds Perchloroethylene Poses an Unreasonable Risk to Human Health
Final Risk Evaluation for Perchloroethylene and related documents
